NADPH & Quinone: Metabolism & Potential Drug Targets (P11350)

Target Name: NAD(P)H dehydrogenase, quinone

NCBI ID: P11350

NAD(P)H dehydrogenase, quinone

Other Name(s): None

NADPH & Quinone: Metabolism & Potential Drug Targets

NAD(P)H dehydrogenase (NADPH dehydrogenase, NADP+-dependent hydrogen production) is a enzyme involved in the final step of the citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, in which NADPH is produced. NADPH is a crucial co-factor for many cellular processes, including the production of ATP, the synthesis of nucleotides, and the detoxification of harmful substances. It is also an essential precursor for the production of the antioxidant NAD+, which is involved in various cellular processes and plays a central role in the fight against oxidative stress.

Quinone (nonspecific subtype), a metabolite of the amino acid tryptophan, is a byproduct of the NADPH synthesis pathway. It has been shown to have various physiological functions, including participating in the regulation of inflammation and cell signaling, and it is also a potent antioxidant. The nonspecific subtype of quinone has been identified as a potential drug target or biomarker due to its unique structure and various biochemical properties.

The NADPH synthesis pathway is a complex process that involves the transfer of electrons from the NAD+ ion to the FAD+ ion, which results in the production of NADPH. The production of NADPH is a critical process for the cell, as it is involved in the production of ATP, the synthesis of nucleotides, and the detoxification of harmful substances. It is also an essential precursor for the production of the antioxidant NAD+, which is involved in various cellular processes and plays a central role in the fight against oxidative stress.

Quinone, as a metabolite of the amino acid tryptophan, is a byproduct of the NADPH synthesis pathway. It has been shown to have various physiological functions, including participating in the regulation of inflammation and cell signaling, and it is also a potent antioxidant. The nonspecific subtype of quinone has been identified as a potential drug target or biomarker due to its unique structure and various biochemical properties.

The production of NADPH is a complex process that involves several steps, including the transfer of electrons from the NAD+ ion to the FAD+ ion. This process results in the production of NADPH, which is then used to produce ATP, the synthesis of nucleotides, and the detoxification of harmful substances. The production of NADPH is essential for the cell, as it is involved in the production of ATP, the synthesis of nucleotides, and the detoxification of harmful substances. It is also an essential precursor for the production of the antioxidant NAD+, which is involved in various cellular processes and plays a central role in the fight against oxidative stress.

Quinone has been shown to have various physiological functions, including participating in the regulation of inflammation and cell signaling. It has been shown to have anti-inflammatory properties, as well as promoting the production of other antioxidants, such as superoxide anion and nitrogen oxidants, which help to protect the cell from oxidative stress. Additionally, quinone has been shown to play a role in cell signaling, as it has been shown to regulate the production of reactive oxygen species (ROS) in the cell.

The nonspecific subtype of quinone has been identified as a potential drug target or biomarker due to its unique structure and various biochemical properties. The structure of quinone allows it to interact with various cellular components and targets, making it a promising drug candidate. Additionally, the unique biochemical properties of quinone, such as its antioxidant and anti-inflammatory properties, make it an attractive target for drug development.

In conclusion, NADPH dehydrogenase and quinone (nonspecific sub

Protein Name: NAD(P)H Dehydrogenase, Quinone (nonspecified Subtype)

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